Artículo
Endocrine function of the surgically reduced pancreas
Fecha de publicación:
1941
Editorial:
The Rockefeller Institute for Medical Research New York
Revista:
Journal of Experimental Medicine
ISSN:
0022-1007
Idioma:
Inglés
Volumen:
74
Número:
3
Páginas:
283-295
Subtipo:
Artículo científico
Financiación:
Fundacion Williams.;
Fundación de Instituto de Biología y Medicina Experimental;
Consejo Nacional de Investigaciones Científicas y Técnicas;
Nombre del Proyecto:
Proyecto Houssay y Leloir
Clasificación temática:
Resumen
The investigations of von Meting and Minkowski (1890) first demonstrated that it is possible to resect large portions of the pancreas without producing diabetes or glycosuria. Minkowski (1890, 1893) found that as little as one-quarter or one-fifth of the pancreas suffices to control glycosuria. Allen (1913) observed that diabetes follows very rarely when one-sixth or one-seventh of the pancreas remains; with an eighth of the pancreas remaining diabetes is mild; if only one-tenth remains the diabetes is pronounced, although in the experimental protocols there were cases without glycosutia in dogs in which only 2 to 3 gin. of pancreas remained. Both Minkowski and Hedon (1898) found that very small portions of the pancreas prevent diabetes, although it was easier to produce alimentary glycosuria in depancreatized than in normal animals.
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Recursos continuos (Bernardo Alberto Houssay)
Recursos continuos (Bernardo Alberto Houssay)
Recursos continuos (Bernardo Alberto Houssay)
Citación
Houssay, Bernardo Alberto; Foglia, Virgilio G.; Smyth, F. S .; Endocrine function of the surgically reduced pancreas; The Rockefeller Institute for Medical Research New York; Journal of Experimental Medicine; 74; 3; 1941; 283-295
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