IGNACIO ESTEBAN LEON

Datos académicos

Lugar de trabajo	CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS / CENTRO CIENTIFICO TECNOLOGICO CONICET - LA PLATA / CENTRO DE QUIMICA INORGANICA "DR. PEDRO J. AYMONINO" \| UNIVERSIDAD NACIONAL DE LA PLATA / FACULTAD DE CS.EXACTAS / CENTRO DE QUIMICA INORGANICA "DR. PEDRO J. AYMONINO"
Título	Metalofármacos de cobre, platino y vanadio. Potencial actividad antitumoral y estudios de mecanismos de acción en modelos in vitro e in vivo
Grado	Universitario de posgrado/doctorado

PRODUCCION CIENTÍFICO TECNOLÓGICA

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Artículo 5‐Nitrofuryl‐Containing Thiosemicarbazone Gold(I) Compounds: Synthesis, Stability Studies, and Anticancer Activity

Rodríguez Arce, Esteban; Gavrilov, Eric; Alvite, Ximena; Nayeem, Nazia; Leon, Ignacio Esteban ; Neary, Michelle C.; Otero, Lucía; Gambino, Dinorah; Olea Azar, Claudio; Contel, María (Wiley, 2023-05)
Artículo 6-Methoxyquinoline complexes as lung carcinoma agents: induction of oxidative damage on A549 monolayer and multicellular spheroid model

Cadavid Vargas, Juan Fernando ; Villa Perez, Cristian ; Ruiz, M. C.; Leon, Ignacio Esteban ; Valencia Uribe, Gloria Cristina; Soria, Delia Beatriz ; Etcheverry, Susana Beatriz ; Di Virgilio, Ana Laura (Springer, 2019-03)
Artículo 8-Hydroxyquinoline platinum(ii) loaded nanostructured lipid carriers: synthesis, physicochemical characterization and evaluation of antitumor activity

Boztepe, Tugce ; Scioli Montoto, Sebastián ; Ruiz, María Esperanza ; Alvarez, Valeria Alejandra; Castro, Guillermo Raul ; Leon, Ignacio Esteban (Royal Society of Chemistry, 2021-01-08)
Artículo A New Oxidovanadium(IV) Complex of Oxodiacetic Acid and dppz: Spectroscopic and DFT Study. Antitumor Action on MG-63 Human Osteosarcoma Cell Line

Leon, Ignacio Esteban ; Parajón Costa, Beatriz Susana ; Franca, Carlos Alberto; Etcheverry, Susana Beatriz ; Baran, Enrique José (Humana Press, 2015-05)
Artículo A Symmetrical Dirhenium(I) Complex with 4,4’’-Azobis(2,2’-bipyridine) as a Bridging Ligand: Synthesis, Physicochemical Properties and Applications in Detection of Biologically Relevant Thiols and in Chemotherapy for Bone Cancer

Abate, Pedro Oscar ; Sottile, Marco; Leon, Ignacio Esteban ; Vergara, Monica Mercedes; Katz, Néstor Eduardo (Sociedade Brasileira de Química, 2020-10)
Artículo Active and pH-sensitive nanopackaging based on polymeric anthocyanin/natural or organo-modified montmorillonite blends: Characterization and assessment of cytotoxicity

Gutiérrez Carmona, Tomy José ; Leon, Ignacio Esteban ; Ponce, Alejandra Graciela ; Alvarez, Vera Alejandra (Multidisciplinary Digital Publishing Institute, 2022-11)
Artículo An Overview of Vanadium and Cell Signaling in Potential Cancer Treatments

Ferretti, Valeria Alejandra; Leon, Ignacio Esteban (Multidisciplinary Digital Publishing Institute, 2022-04)
Artículo Anticancer Activity and Mechanism of Action Evaluation of an Acylhydrazone Cu(II) Complex toward Breast Cancer Cells, Spheroids, and Mammospheres

Balsa, Lucia Mariana ; Rodríguez, María Rosa ; Parajón Costa, Beatriz Susana ; Gonzalez Baro, Ana Cecilia ; Lavecchia, Martín José ; Leon, Ignacio Esteban (Wiley VCH Verlag, 2021-11)
Artículo Anticancer activity of a new copper(ii) complex with a hydrazone ligand. Structural and spectroscopic characterization, computational simulations and cell mechanistic studies on 2D and 3D breast cancer cell models

Balsa, Lucia Mariana ; Ferraresi Curotto, Verónica ; Lavecchia, Martín José ; Echeverría, Gustavo Alberto ; Piro, Oscar Enrique ; García Tojal, Javier; Pis Diez, Reinaldo ; Gonzalez Baro, Ana Cecilia ; Leon, Ignacio Esteban (Royal Society of Chemistry, 2021-03)
Artículo Anticancer activity of Ni(ii) and Zn(ii) complexes based on new unsymmetrical salophen-type ligands: synthesis, characterization and single-crystal X-ray diffraction

Villaman, David; Vega, Andrés; Santa Maria de la Parra, Lucía ; Leon, Ignacio Esteban ; Levín, Pedro; Toro, Patricia M. (Royal Society of Chemistry, 2023-07)
Artículo Anticancer and Antimetastatic Activity of Copper(II)-tropolone complex against human breast cancer cells, breast multicellular spheroids and mammospheres

Balsa, Lucia Mariana ; Ruiz, Maria Carolina ; Santa Maria de la Parra, Lucía ; Baran, Enrique José ; Leon, Ignacio Esteban (Elsevier Science Inc, 2020-03)
Artículo Anticancer and Antioxidant Activity of Water-Soluble Polysaccharides from Ganoderma aff. australe against Human Osteosarcoma Cells

Muñoz Castiblanco, Tatiana; Santa Maria de la Parra, Lucía ; Peña Cañón, Rocio; Mejía Giraldo, Juan Camilo; Leon, Ignacio Esteban ; Puertas Mejía, Miguel Ángel (Multidisciplinary Digital Publishing Institute, 2022-12)
Artículo Antiproliferative activity of two copper (II) complexes on colorectal cancer cell models: Impact on ROS production, apoptosis induction and NF-κB inhibition

Ruiz, Maria Carolina ; Perelmulter, Karen; Levín, Pedro; Romo, Adolfo I.B.; Lemus, Luis; Bollati Fogolín, Mariela; Leon, Ignacio Esteban ; Di Virgilio, Ana Laura (Elsevier Science, 2022-02)
Artículo Antiproliferative and apoptosis-inducing activity of an oxidovanadium(IV) complex with the flavonoid silibinin against osteosarcoma cells

Leon, Ignacio Esteban ; Porro, V; Di Virgilio, Ana Laura ; Naso, Luciana Gissella ; Williams, Patricia Ana María; Bollati Fogolin, M.; Etcheverry, Susana Beatriz (Springer, 2014-02)
Artículo Antitumor properties of a vanadyl(IV) complex with the flavonoid chrysin [VO(chrysin)2EtOH]2 in a human osteosarcoma model: the role of oxidative stress and apoptosis

Leon, Ignacio Esteban ; Di Virgilio, Ana Laura ; Porro, V.; Muglia, Cecilia Isabel ; Naso, Luciana Gissella ; Williams, P. A. M.; Bollati Fogolin, M.; Etcheverry, Susana Beatriz (Royal Society of Chemistry, 2013-05)
Artículo Artificial chemical nuclease and cytotoxic activity of a mononuclear copper(I) complex and a related binuclear double-stranded helicate

Levín, Pedro; Balsa, Lucia Mariana ; Silva, Carlos P.; Herzog, Austin E.; Vega, Andrés; Pavez, Jorge; Leon, Ignacio Esteban ; Lemus, Luis (Wiley VCH Verlag, 2021-09)
Artículo Bacterial cellulose hydrogel loaded with lipid nanoparticles for localized cancer treatment

Cacicedo, Maximiliano Luis ; Islan, German Abel ; Leon, Ignacio Esteban ; Alvarez, Vera Alejandra ; Chourpa, Igor; Allard Vannier, E.; García Aranda, N.; Díaz Riascos, Z.V.; Fernández, Y.; Schwartz, S.; Abasolo, Ibane; Castro, Guillermo Raul (Elsevier Science, 2018-10)
Artículo Bis(oxalato)dioxovanadate(V) and Bis(oxalato)oxoperoxo-vanadate(V) Complexes: Spectroscopic Characterization and Biological Activity

Leon, Ignacio Esteban ; Etcheverry, Susana Beatriz ; Parajón Costa, Beatriz Susana ; Baran, Enrique José (Humana Press, 2013-09-12)
Artículo Chrysin-loaded bovine serum albumin particles as bioactive nanosupplements

Ferrado, Joana Belén ; Perez, Adrián Alejandro ; Ruiz, Maria Carolina ; Leon, Ignacio Esteban ; Santiago, Liliana Gabriela (Royal Society of Chemistry, 2020-05)
Artículo Comparative antitumor studies of organoruthenium complexes with 8-hydroxyquinolines on 2D and 3D cell models of bone, lung and breast cancer

Ruiz, Maria C.; Kljun, Jakob; Turel, Iztok; Di Virgilio, Ana Laura ; Leon, Ignacio Esteban (Royal Society of Chemistry, 2019-03)

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